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Re: Coolant disposal debate, ad nauseum

To: "Datsun Roadster Mailing list" <datsun-roadsters@autox.team.net>
Subject: Re: Coolant disposal debate, ad nauseum
From: snyler <marc@animalfirm.com>
Date: Mon, 9 Jul 2001 15:48:13 -0500
Alex Avery wrote

> 
>For you really die-hard science geeks (like me) here are the details of
>mammalian ethylene glycol toxicity: The metabolites inhibit oxidative
>phosphorylation, sulfhydrl-containing enzymes, and protein synthesis.
>Glycolic acid is the major cause of the metabolic acidosis that is seen in
>ethylene glycol toxicity, although glyoxylic acid also may contribute.
>Toxicity from ethylene glycol is produced from the above metabolites and
>the fact that they cause a severe acidosis, as well as from the fact that
>oxalate precipitates with calcium to produce widespread tissue injury in
>the kidney, brain, liver, blood vessels, and pericardium. Hypocalcemia may
>also result. 
>
>Sorry for the length but I really hate misinformation and love scientific
>stuff like this.
>Alex Avery
>Director of Research
>Hudson Institute
>Center for Global Food Issues
>'78 280Z and caretaker of dad's SRL311-7278
>
What about invertebrate toxicity?  And other vertebrates Amphibians, 
reptiles, birds, etc.  Thanks, by the way.  

-Marc

==========================================================================
Marc Tyler
Designer,
Animal Firm
830-324-6578
www.animalfirm.com

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